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| Description |
| Mouse CD11b MicroBeads are used for the depletion or positive selection of mouse (or human) macrophages and monocytes from lymphoid and non-lymphoid tissue or blood. CD11b is expressed on macrophages/monocytes and to a lower extent on granulocytes, NK cells, and subsets of dendritic cells. |
| Applications |
| CD11b MicroBeads have been used to isolate CD11b+ cells from cell suspensions of spleen1, lymph node2, peritoneal cavity3, liver4, muscle tissue2, or blood5. They were also used in combination with other MicroBeads for the enrichment of mast cells from peritoneal cell suspensions.3 |
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| Figure 1 |
| Positive selection of CD11b+ cells from a mouse spleen cell suspension using CD11b MicroBeads, an MS Column, and a MiniMACS™ Separator. |
| Spleen cells before separation |
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| Spleen cells after depletion of CD11b+ cells |
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| Isolated CD11b+ mouse cells |
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| Products |
| CD11b MicroBeads, human and mouse |
- for 1×109 total human cells, or for 2×109 total mouse cells
Download datasheet
130-049-601
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| References |
| 1. Lohoff et al. (1997) Immunity 6: 681–689. |
| 2. Dupuis et al. (2000) J. Immunol. 165: 2850–2858. |
| 3. Chen et al. (1999) Immunol. 96: 544–550. |
| 4. Do et al. (1999) J. Biol. Chem. 274: 19587–19592. |
| 5. Mathy et al. (2000) J. Immunol. 164: 4429–4432. |
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