MACS® GMP Recombinant Human IL-6
Description Interleukin 6 (IL-6) is a cytokine showing growth-inducing, growth-inhibitory, and differentiation-inducing effects in a cell type–specific manner. IL-6 acts as both a pro-inflammatory and anti-inflammatory cytokine. It is mainly produced by monocytes and macrophages, but as well by epithelial or endothelial cells. IL-6 is one of the most important mediators of fever and of the acute phase response affecting B lymphocytes, T lymphocytes, and hybridoma cells. In combination with other factors like human interleukin 2 and interferon γ it also affects cytotoxic T lymphocytes. MACS GMP Recombinant Human IL-6 is lyophilized without carrier protein or preservatives. A lot-specific certificate confirms identity, molecular mass, specific activity, sterility, purity, endotoxin content, and host-cell DNA content. Applications MACS GMP Recombinant Human IL-6 can be used for a variety of applications, including the ex vivo generation of human dendritic cells from enriched CD14+ monocytes.1-3 MACS GMP Recombinant Human IL-6 is not intended for human in vivo application. Quality Statement MACS GMP Recombinant Human IL-6 may be used for research or ex vivo cell culture processing. MACS GMP Recombinant Human IL-6 is manufactured and tested under a certified ISO 9001 quality system and in compliance with relevant GMP guidelines. It is designed following the recommendations of USP <1043> on ancillary materials. No animal- or human-derived components are used for manufacturing.

Search this website

Advanced search