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| Description |
Clone LT20 recognizes the human CD20 antigen, a non-glycosylated transmembrane protein of 33–37 kDa that is expressed on B lineage cells from the pre-B cell stage to the B cell lymphoblast stage. The antigen is further expressed on most malignant B cells. CD20 is not found on early B cell progenitors or plasma cells. Oligomers of CD20 form a Ca2+ channel and might function in the regulation of local responses during B cell activation. The VioBlue-conjugated CD20 antibody requires the use of a violet laser. |
| Applications |
The CD20 antibody can be used to identify and enumerate CD20+ B cells by flow cytometry or fluorescence microscopy. This antibody is suitable for use in MACS® Control applications. For further details, please refer to the data sheet of the separation reagent. |
| Cross-reactivity |
- Rhesus monkey (Macaca mulatta)
- Cynomolgus monkey (Macaca fascicularis)
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| Clone | Isotype |
| LT20 | Mouse IgG1 |
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| Figure 1 |
| Human peripheral blood lymphocytes were stained with CD20-FITC (A), CD20-PE (B), CD20-VioBlue (C), or CD20-PerCP (D) and analyzed by flow cytometry. |
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| B |
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| C |
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| D |
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| Products |
| CD20-FITC, human |
- for 100 tests (1) Download datasheet 130-091-108
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| CD20-PE, human |
- for 100 tests (1) Download datasheet 130-091-109
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| CD20-VioBlue, human |
- for 100 tests (1) Download datasheet 130-094-167
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| CD20-PerCP, human |
- for 100 tests (1) Download datasheet 130-094-976
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 μL. |
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