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Hematopoietic stem and progenitor cells
<b>Hematopoietic stem and progenitor cells</b>
Hematopoietic stem and progenitor cell (HSC/HPC) research has contributed a great deal to the understanding and harnessing of hematopoieisis for use within therapeutic research applications.

Miltenyi Biotec provides integrated product solutions for cutting-edge human hematopoietic stem and progenitor cell research. All products for human HSCs/HPCs research have been optimized for direct use with one another, meaning that isolation, cultivation, and analysis of HSCs can be performed in a standardized, seamless process.

Cell separation
A broad range of high-quality cell separation reagents are available, for example for the selection of:
• HSCs/HPCs using CD34, CD133, CD117 MicroBeads or the Lineage Cell Depletion Kit
• Lineage-committed progenitor cells using CD33 or CD71 MicroBeads

Cell analysis
Miltenyi Biotec offers a wide range of products for the analysis of human cells by flow cytometry or fluorescence microscopy, including a panel of unique and standard monoclonal antibodies for HSC/HPC research, such as CD34, CD133, CD117, CD33, and CD71.

Cell culture
A broad range of specially developed HSC-CFU media for the functional characterization and enumeration of HSCs/HPCs are available. MACS® HSC-CFU Media are standardized semi-solid media that provide reliable and reproducible results for the colony assays of HSCs.

Gene expression profiling
Topic-defined PIQOR™ Stem Cell Microarrays* and services for gene expression profiling of stem cells. Also available: Single-cell gene expression profiling SuperAmp™ Service** for the amplification of RNA from 1 to 100,000 cells sorted by flow cytometry, laser capture microdissection, primary cells, or tissue biopsies.

Click here for an overview of the expression pattern of CD133 and CD34 during hematopoietic development.

Click here to download a brochure describing in-depth all Miltenyi Biotec products for human hematopietic stem cell research.


For information on products for mouse stem cell research, click here.

* PIQOR™ Microarrays Kits are not available in the US and Canada.
** In combination with the Microarray Service only.
Details and background information
Human HSC Flyer [PDF, 872 KB]
HSC – reference list [PDF, 115 KB]
HSC-CFU media poster Watts 2008 [PDF, 269 KB]
CD34 MicroBead Kit
ProductApplicationsorder no.
CD34 MicroBead Kit, humanPositive selection of human hematopoietic stem and progenitor cells130-046-702
CD34 MicroBead Kit, humanPositive selection of human hematopoietic stem and progenitor cells130-046-703
Indirect CD34 MicroBead Kit
ProductApplicationsorder no.
Indirect CD34 MicroBead Kit, humanPositive selection of human hematopoietic stem and progenitor cells130-046-701
CD34 MultiSort Kit
ProductApplicationsorder no.
CD34 MultiSort Kit, humanIsolation of human CD34+ cell subsets130-056-701
CD133 MicroBead Kit
ProductApplicationsorder no.
CD133 MicroBead Kit, humanPositive selection of human CD133+ stem and progenitor cells130-050-801
Indirect CD133 MicroBead Kit
ProductApplicationsorder no.
Indirect CD133 MicroBead Kit, humanPositive selection of human CD133+ stem and progenitor cells130-091-895
CD117 MicroBead Kit
ProductApplicationsorder no.
CD117 MicroBead Kit, humanPositive selection of human CD117 (c-kit)+ cells130-091-332
Lineage Cell Depletion Kit
ProductApplicationsorder no.
Lineage Cell Depletion Kit, humanKit for the enrichment of untouched human stem and progenitor cells130-092-211
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