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Mesenchymal stromal cells
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Mesenchymal stromal cells (MSCs) are fibroblast-like plastic-adherent cells that can be isolated from a variety of tissues, such as bone marrow, periosteum, trabecular bone, adipose tissue, synovium, skeletal muscle, dental pulp.
MSC research may provide the basis for a variety of potential clinical applications:
- Tissue regeneration
- Immunomodulation
- Expansion of HSCs in vitro
- Improved engraftment of HSCs
- Delivery vehicle, e.g., for potential treatment of cancer or genetic disorders
To investigate the capability of MSCs in clinical applications, it is crucial to standardize their isolation and culture methods. Miltenyi Biotec has developed numerous tools and several protocols for MSC research.
Sample preparation
NEW: A special protocol for the isolation of MSCs/ADSCs from human lipoaspirate is now available. Click here to download the PDF version of the protocol.
Isolation and analysis according to various markers.
Expansion and differentiation of MSCs
microRNA and gene expression profiling and services
Stem cell–specific miRNA and gene expression profiling can be performed using miRXplore™ Microarray Kits and Services
PIQOR™ Stem Cell Microarrays* and Services
Single-cell gene expression profiling SuperAmp™ Service**:
for the amplification of RNA from 1 to 100,000 cells sorted by flow cytometry, laser capture microdissection, primary cells, or tissue biopsies.
For information on products for mouse stem cell research, please click here.
* PIQOR™ Microarrays Kits are not available in the US and Canada.
** In combination with the Microarray Service only. |
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| MSC Research Tool Box - CD271 (LNGFR) |
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| CD271 (LNGFR) MicroBead Kit |
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| MSC Research Tool Box - MSCA-1 (W8B2) |
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| Anti-MSCA-1 (W8B2) MicroBead Kit |
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| Indirect CD133 MicroBead Kit |
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| CD105 MicroBeads |
| Product | Applications | order no. |
| CD105 MicroBeads, human | Positive selection of human mesenchymal stromal cells (MSCs) from bone marrow aspirate. | 130-051-201 |
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| Anti-Fibroblast MicroBeads |
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| Lineage Cell Depletion Kit |
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